B-chromosome evolution

Juan Pedro M. Camacho, Timothy F. Sharbel, Leo W. Beukeboom

OnderzoeksoutputAcademicpeer review

534 Citaten (Scopus)
339 Downloads (Pure)


B chromosomes are extra chromosomes to the standard complement that occur in many organisms. They can originate in a number of ways including derivation from autosomes and sex chromosomes in intra- and interspecies crosses. Their subsequent molecular evolution resembles that of univalent sex chromosomes, which involves gene silencing, heterochromatinization and the accumulation of repetitive DNA and transposons. B-chromosome frequencies in populations result from a balance between their transmission rates and their e¡ects on host ¢tness. Their long-term evolution is considered to be the outcome of selection on the host genome to eliminate B chromosomes or suppress their e¡ects and on the B chromosome’s ability to escape through the generation of new variants. Because B chromosomes interact with the standard chromosomes, they can play an important role in genome evolution and may be useful for studying molecular evolutionary processes.
Originele taal-2English
Pagina's (van-tot)163-178
Aantal pagina's16
TijdschriftPhilosophical Transactions of the Royal Society of London B
Nummer van het tijdschrift1394
StatusPublished - 2000

Citeer dit