Bile Acid Look-Alike Controls Life Span in C. elegans

Albert K. Groen*, Folkert Kuipers

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

6 Citaten (Scopus)

Samenvatting

Extensive transcriptional networks maintain sterol homeostasis across species, underscoring the importance of sterol balance for healthy life. Magner et al. (2013) now show that, in C. elegans, the nuclear receptor NHR-8 is key in regulation of cholesterol balance and production of dafachronic acid, a bile acid-like steroid that controls longevity.

Originele taal-2English
Pagina's (van-tot)151-152
Aantal pagina's3
TijdschriftCell metabolism
Volume18
Nummer van het tijdschrift2
DOI's
StatusPublished - 6-aug-2013

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