Biomarkers of Renal Function: Towards Clinical Actionability

S Heleen Binnenmars; R S Hijmans; G Navis; M H de Borst

doi:10.1002/cpt.765

Biomarkers of Renal Function: Towards Clinical Actionability

S Heleen Binnenmars, R S Hijmans, G Navis, M H de Borst

Onderzoeksoutput: Review article › peer review

11 Citaten (Scopus)

112 Downloads (Pure)

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This review provides an overview of the clinical value of themost relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.

Originele taal-2	English
Pagina's (van-tot)	481-492
Aantal pagina's	12
Tijdschrift	Clinical Pharmacology & Therapeutics
Volume	102
Nummer van het tijdschrift	3
DOI's	https://doi.org/10.1002/cpt.765
Status	Published - sep.-2017

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10.1002/cpt.765

Biomarkers of Renal Function: Towards Clinical ActionabilityFinal publisher's version, 187 KBLicentie: Taverne

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@article{57cd6dd689804704882dbaa9eaff5907,

title = "Biomarkers of Renal Function: Towards Clinical Actionability",

abstract = "This review provides an overview of the clinical value of themost relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.",

keywords = "ACUTE KIDNEY INJURY, GELATINASE-ASSOCIATED LIPOCALIN, INDIVIDUAL PARTICIPANT DATA, DIETARY-SODIUM RESTRICTION, GLOMERULAR-FILTRATION-RATE, CYCLE ARREST BIOMARKERS, COLLABORATIVE METAANALYSIS, CARDIAC-SURGERY, CYSTATIN-C, DISEASE PROGRESSION",

author = "Binnenmars, \{S Heleen\} and Hijmans, \{R S\} and G Navis and \{de Borst\}, \{M H\}",

note = "{\textcopyright} 2017 American Society for Clinical Pharmacology and Therapeutics.",

year = "2017",

month = sep,

doi = "10.1002/cpt.765",

language = "English",

volume = "102",

pages = "481--492",

journal = "Clinical Pharmacology \& Therapeutics",

issn = "0009-9236",

publisher = "Nature Publishing Group",

number = "3",

}

TY - JOUR

T1 - Biomarkers of Renal Function

T2 - Towards Clinical Actionability

AU - Binnenmars, S Heleen

AU - Hijmans, R S

AU - Navis, G

AU - de Borst, M H

PY - 2017/9

Y1 - 2017/9

N2 - This review provides an overview of the clinical value of themost relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.

AB - This review provides an overview of the clinical value of themost relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.

KW - ACUTE KIDNEY INJURY

KW - GELATINASE-ASSOCIATED LIPOCALIN

KW - INDIVIDUAL PARTICIPANT DATA

KW - DIETARY-SODIUM RESTRICTION

KW - GLOMERULAR-FILTRATION-RATE

KW - CYCLE ARREST BIOMARKERS

KW - COLLABORATIVE METAANALYSIS

KW - CARDIAC-SURGERY

KW - CYSTATIN-C

KW - DISEASE PROGRESSION

U2 - 10.1002/cpt.765

DO - 10.1002/cpt.765

M3 - Review article

C2 - 28608458

SN - 0009-9236

VL - 102

SP - 481

EP - 492

JO - Clinical Pharmacology & Therapeutics

JF - Clinical Pharmacology & Therapeutics

IS - 3

ER -

Biomarkers of Renal Function: Towards Clinical Actionability

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