Samenvatting
Processing of miRNAs occurs simultaneous with the transcription and splicing of their primary transcripts. For the small subset of exonic miRNAs it is unclear if the unspliced and/or spliced transcripts are used for miRNA biogenesis. We assessed endogenous levels and cellular location of primary transcripts of three exonic miRNAs. The ratio between unspliced and spliced transcripts varied markedly, i.e. >1 for BIC,
Originele taal-2 | English |
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Artikelnummer | e76647 |
Aantal pagina's | 11 |
Tijdschrift | PLoS ONE |
Volume | 8 |
Nummer van het tijdschrift | 9 |
DOI's | |
Status | Published - 20-sep.-2013 |