Challenges of diagnosing glaucoma in myopic eyes: Characteristics and determinants of the anatomical structures relevant to glaucoma

Kunliang Qiu

Challenges of diagnosing glaucoma in myopic eyes: Characteristics and determinants of the anatomical structures relevant to glaucoma

Vertaalde titel van de bijdrage: Uitdagingen bij het diagnosticeren van glaucoom bij bijziende mensen: kenmerken en determinanten van de anatomische structuren die relevant zijn voor glaucoom

Kunliang Qiu

Onderzoeksoutput

2056 Downloads (Pure)

Samenvatting

Bijziendheid is een veelvoorkomende aandoening in de wereld en een belangrijke risicofactor voor glaucoom. Glaucoom is een aandoening waarbij de oogzenuw geleidelijk afsterft en het gezichtsveld beperkt wordt; onomkeerbare blindheid kan het gevolg zijn indien niet tijdig een behandeling wordt ingesteld. Het diagnosticeren van glaucoom bij bijzienden is moeilijk, omdat bijziende ogen vaak anatomische kenmerken hebben, en afwijkingen aan het gezichtsveld vertonen, die sterk lijken op de veranderingen die je ziet bij ogen met glaucoom. Daarom is een gedetailleerd begrip van de anatomische structuren die relevant zijn voor glaucoom van groot belang. Dit proefschrift heeft als titel "Uitdagingen bij het diagnosticeren van glaucoom bij bijziende mensen". Kern van het onderzoek is de OCT techniek (optical coherence tomography), een techniek waarmee de anatomie van de structuren in het oog in detail kunnen worden bestudeerd. Structuren relevant voor glaucoom zijn onder andere de retinale zenuwvezellaag (retinal nerve fiber layer; RNFL) en de ganglioncellaag in de macula (gele vlek). Bij de RNFL gaat het zowel om het dikteprofiel rond de papil (peripapillaire RNFL; de papil is de plaats waar de zenuwvezels het oog verlaten en de oogzenuw vormen) als om het verloop van de zenuwvezelbundels over de retina (het netvlies). Ik vond een aantal kenmerkende verschillen tussen bijziendheid en glaucoom die het voor de oogarts makkelijker maken een goed onderscheid te maken tussen beide oogziektes.

Vertaalde titel van de bijdrage	Uitdagingen bij het diagnosticeren van glaucoom bij bijziende mensen: kenmerken en determinanten van de anatomische structuren die relevant zijn voor glaucoom
Originele taal-2	English
Kwalificatie	Doctor of Philosophy
Toekennende instantie	Rijksuniversiteit Groningen
Begeleider(s)/adviseur	Jansonius, Nomdo, Supervisor Cornelissen, Frans, Supervisor Verkerke, Gijsbertus, Beoordelingscommissie Webers, Carroll A., Beoordelingscommissie, Externe Persoon Vass, C., Beoordelingscommissie, Externe Persoon
Datum van toekenning	23-apr.-2018
Plaats van publicatie	[Groningen]
Uitgever	University of Groningen
Gedrukte ISBN's	978-94-034-0613-8
Elektronische ISBN's	978-94-034-0612-1
Status	Published - 2018

Toegang tot document

Title and contentsFinal publisher's version, 190 KB
Chapter 1Final publisher's version, 965 KB
Chapter 2Final publisher's version, 733 KB
Chapter 3Final publisher's version, 818 KB
Chapter 4Final publisher's version, 490 KB
Chapter 5Final publisher's version, 481 KB
Chapter 6Final publisher's version, 697 KB
Chapter 7Final publisher's version, 416 KB
Chapter 8Final publisher's version, 619 KB
Chapter 9Final publisher's version, 403 KB
Chapter 10Final publisher's version, 208 KB
AppendicesFinal publisher's version, 197 KB
Complete thesisFinal publisher's version, 3,77 MB
PropositionsFinal publisher's version, 87,7 KB

Handle.net

Permanente koppeling

Citeer dit

@phdthesis{b9bf1712708f4044bf38d567d44a199c,

title = "Challenges of diagnosing glaucoma in myopic eyes: Characteristics and determinants of the anatomical structures relevant to glaucoma",

abstract = "Myopia is a common condition in the world and a major risk factor for glaucoma. Glaucoma is a condition in which the optic nerve gradually dies and the visual fields shrinks; irreversible blindness may result if treatment is not initiated on time. Diagnosing glaucoma in myopic people is difficult because myopic eyes often have anatomical features and visual field defects that are very similar to the changes you may observe in eyes with glaucoma. Therefore, a detailed understanding of the anatomical structures relevant to glaucoma is of great importance. This thesis is entitled {"}Challenges in diagnosing glaucoma in myopic eyes{"}. The core of the research is the OCT technique (optical coherence tomography), a technique with which the anatomy of the structures in the eye can be studied in detail. Structures relevant to glaucoma include the retinal nerve fiber layer (RNFL) and the ganglion cell layer in the macula. The RNFL involves both the thickness profile around the optic nerve head (peripapillary RNFL, the optic nerve head is where the nerve fibers leave the eye and form the optic nerve) and the trajectories of the nerve fiber bundles over the retina. I found a number of characteristic differences between myopia and glaucoma that make it easier for the ophthalmologist to make a good distinction between these two eye diseases.",

author = "Kunliang Qiu",

year = "2018",

language = "English",

isbn = "978-94-034-0613-8",

publisher = "University of Groningen",

school = "University of Groningen",

}

TY - BOOK

T1 - Challenges of diagnosing glaucoma in myopic eyes

T2 - Characteristics and determinants of the anatomical structures relevant to glaucoma

AU - Qiu, Kunliang

PY - 2018

Y1 - 2018

N2 - Myopia is a common condition in the world and a major risk factor for glaucoma. Glaucoma is a condition in which the optic nerve gradually dies and the visual fields shrinks; irreversible blindness may result if treatment is not initiated on time. Diagnosing glaucoma in myopic people is difficult because myopic eyes often have anatomical features and visual field defects that are very similar to the changes you may observe in eyes with glaucoma. Therefore, a detailed understanding of the anatomical structures relevant to glaucoma is of great importance. This thesis is entitled "Challenges in diagnosing glaucoma in myopic eyes". The core of the research is the OCT technique (optical coherence tomography), a technique with which the anatomy of the structures in the eye can be studied in detail. Structures relevant to glaucoma include the retinal nerve fiber layer (RNFL) and the ganglion cell layer in the macula. The RNFL involves both the thickness profile around the optic nerve head (peripapillary RNFL, the optic nerve head is where the nerve fibers leave the eye and form the optic nerve) and the trajectories of the nerve fiber bundles over the retina. I found a number of characteristic differences between myopia and glaucoma that make it easier for the ophthalmologist to make a good distinction between these two eye diseases.

AB - Myopia is a common condition in the world and a major risk factor for glaucoma. Glaucoma is a condition in which the optic nerve gradually dies and the visual fields shrinks; irreversible blindness may result if treatment is not initiated on time. Diagnosing glaucoma in myopic people is difficult because myopic eyes often have anatomical features and visual field defects that are very similar to the changes you may observe in eyes with glaucoma. Therefore, a detailed understanding of the anatomical structures relevant to glaucoma is of great importance. This thesis is entitled "Challenges in diagnosing glaucoma in myopic eyes". The core of the research is the OCT technique (optical coherence tomography), a technique with which the anatomy of the structures in the eye can be studied in detail. Structures relevant to glaucoma include the retinal nerve fiber layer (RNFL) and the ganglion cell layer in the macula. The RNFL involves both the thickness profile around the optic nerve head (peripapillary RNFL, the optic nerve head is where the nerve fibers leave the eye and form the optic nerve) and the trajectories of the nerve fiber bundles over the retina. I found a number of characteristic differences between myopia and glaucoma that make it easier for the ophthalmologist to make a good distinction between these two eye diseases.

M3 - Thesis fully internal (DIV)

SN - 978-94-034-0613-8

PB - University of Groningen

CY - [Groningen]

ER -

Challenges of diagnosing glaucoma in myopic eyes: Characteristics and determinants of the anatomical structures relevant to glaucoma

Samenvatting

Toegang tot document

Handle.net

Vingerafdruk

Citeer dit