Chemical approaches for quantitative proteomics

Xiaobo Tian

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Samenvatting

Xiaobo focuses on developing novel isotope labeling-based tags for quantitative proteomics along two lines of research: (1) In data-dependent acquisition (DDA) mode, eliminating the ratio distortion caused by peptide cofragmentation and increasing the multiplexing capacity. (2) In data-independent acquisition (DIA) mode, achieving multiplexed quantification with general DIA LC-MS settings. The representative work, Ac-IP tag that specifically suitable for the multiplexing in DIA mode, attracted much attention from peers.
Originele taal-2English
KwalificatieDoctor of Philosophy
Toekennende instantie
  • Rijksuniversiteit Groningen
Begeleider(s)/adviseur
  • Bischoff, Rainer, Supervisor
  • Permentier, Hjalmar, Co-supervisor
Datum van toekenning24-sep-2021
Plaats van publicatie[Groningen]
Uitgever
DOI's
StatusPublished - 2021

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