Chromanol, quinone or hydroquinone compounds for treatment of sepsis

Hjalmar Roland Bouma; Guido Krenning; Robert Henk Henning; Adrianus Cornelis van der Graaf

Chromanol, quinone or hydroquinone compounds for treatment of sepsis

Hjalmar Roland Bouma (Uitvinder), Guido Krenning (Uitvinder), Robert Henk Henning (Uitvinder), Adrianus Cornelis van der Graaf (Uitvinder)

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The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of sepsis and sepsis-induced organ dysfunction. Specifically, the present invention relates to chromanol compounds chosen from S-(6-hydroxy-2,5,7,8- tetramethylchroman-2yl)(piperazin-1-yl)methanone and S-(6-hydroxy-2,5,7,8- tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone, and pharmaceutically acceptable salts thereof.

Originele taal-2	English
Octrooinummer	WO2021246868
Prioriteitsdatum	02/06/2020
Indieningsdatum	02/06/2021
Status	Published - 9-dec.-2021

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title = "Chromanol, quinone or hydroquinone compounds for treatment of sepsis",

abstract = "The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of sepsis and sepsis-induced organ dysfunction. Specifically, the present invention relates to chromanol compounds chosen from S-(6-hydroxy-2,5,7,8- tetramethylchroman-2yl)(piperazin-1-yl)methanone and S-(6-hydroxy-2,5,7,8- tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone, and pharmaceutically acceptable salts thereof.",

author = "Bouma, {Hjalmar Roland} and Guido Krenning and Henning, {Robert Henk} and {van der Graaf}, {Adrianus Cornelis}",

year = "2021",

month = dec,

day = "9",

language = "English",

type = "Patent",

note = "WO2021246868",

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TY - PAT

T1 - Chromanol, quinone or hydroquinone compounds for treatment of sepsis

AU - Bouma, Hjalmar Roland

AU - Krenning, Guido

AU - Henning, Robert Henk

AU - van der Graaf, Adrianus Cornelis

PY - 2021/12/9

Y1 - 2021/12/9

N2 - The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of sepsis and sepsis-induced organ dysfunction. Specifically, the present invention relates to chromanol compounds chosen from S-(6-hydroxy-2,5,7,8- tetramethylchroman-2yl)(piperazin-1-yl)methanone and S-(6-hydroxy-2,5,7,8- tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone, and pharmaceutically acceptable salts thereof.

AB - The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of sepsis and sepsis-induced organ dysfunction. Specifically, the present invention relates to chromanol compounds chosen from S-(6-hydroxy-2,5,7,8- tetramethylchroman-2yl)(piperazin-1-yl)methanone and S-(6-hydroxy-2,5,7,8- tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone, and pharmaceutically acceptable salts thereof.

M3 - Patent

M1 - WO2021246868

Y2 - 2021/06/02

ER -

Chromanol, quinone or hydroquinone compounds for treatment of sepsis

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