The Cerebrovascular Accident (CVA) still remains a significant cause of morbidity and mortality. A CVA is caused by occlusion or bleeding of one of the cerebral vessels. Following a CV A the patient usually presents with sudden clinical symptoms of paresis of one of the limbs, speech impairment, partial blindness or feelings of numbness in certain parts of the body. Until now few therapeutic strategies have been available for except stabilisation of the patient and provision of nursing. Considering the huge socio-economic impact of the CVA (incidence of 150 to 250 per 100,000 inhabitants per year and direct costs per patient from first stroke to death of $ 30,000) extensive research has been carried out to develop therapeutiC strategies. To the present time, only thrombolytic therapy with r-TP A has been shown to be successful in certain patient groups. Several risk factors have been identified in the pathogenesis of stroke. Among these, hypertension is considered the most important treatable factor. ...
|Kwalificatie||Doctor of Philosophy|
|Datum van toekenning||17-jun-1998|
|Status||Published - 1998|