TY - PAT
T1 - Compacted Solid Dosage Form
AU - Frijlink, Henderik Willem
AU - Grasmeijer, Niels
AU - Hinrichs, Wouter Leonardus Joseph
AU - Amssoms, Katie Ingrid Eduard
AU - Baert, Lieven Elvire Colette
PY - 2016/2/11
Y1 - 2016/2/11
N2 - The present invention relates to dosage forms comprising a compressed blend of a biologically active ingredient, one or more polymers like a poly(α-hydroxy carboxylic acid) in which optionally is incorporated a glass transition modifying agent, and optional further ingredients, wherein the polymer or polymeric mixture has a specific glass transition temperature which causes the system to be in the glassy state at ambient conditions before administration and to be in the rubbery state under the physiological conditions to which the system is exposed after administration, resulting in pulsed release of said biologically active ingredient.
AB - The present invention relates to dosage forms comprising a compressed blend of a biologically active ingredient, one or more polymers like a poly(α-hydroxy carboxylic acid) in which optionally is incorporated a glass transition modifying agent, and optional further ingredients, wherein the polymer or polymeric mixture has a specific glass transition temperature which causes the system to be in the glassy state at ambient conditions before administration and to be in the rubbery state under the physiological conditions to which the system is exposed after administration, resulting in pulsed release of said biologically active ingredient.
M3 - Patent
M1 - WO2016020308
ER -