Compounds for treatment of alzheimer’s disease

Robert Henk Henning (Uitvinder), Adrianus Cornelis Van der Graaf (Uitvinder), Guido Krenning (Uitvinder), Daniel Swart (Uitvinder), Christina Francoise de Veij Mestdagh (Uitvinder), Pieter Cornelis Vogelaar (Uitvinder)

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The invention relates to certain chromanol, quinone or hydroquinone compounds and ‘ derivatives thereof for treatment of Alzheimer’s disease and/or for improving memory , function. Specifically, the present invention relates to chromanol compounds chosen from (6— \ 5 hydroxy-2,5,7,8—tetramethylchroman—Zyl)(piperazin-l -yl)methanone, ((S)-6-hydroxy-2,5,7,8~ tetramethyl—N—((R)-piperidin—3—yl)chroman—2—carboxamide hydrochloride and S-(6—hydroxy— 2,5 ,7, 8~tetramethylchroman—2-yl)(4-(2—hydroxyethyl)piperazin- 1 -y1)methanone, and pharmaceutically acceptable salts thereof.
Originele taal-2English
OctrooinummerWO2021118359
Prioriteitsdatum11/12/2019
Indieningsdatum11/12/2020
StatusPublished - 17-jun.-2021

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