Copper-free 'click': 1,3-dipolar cycloaddition of azides and arynes

Lachlan Campbell-Verduyn, Philip H. Elsinga, Leila Mirfeizi, Rudi A. Dierckx, Ben L. Feringa*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

94 Citaten (Scopus)
37 Downloads (Pure)


Arynes formed through fluoride-promoted ortho-elimination of o-(trimethylsilyl)aryl triflates can undergo [3 + 2] cycloaddition with various azides to form substituted benzotriazoles. The rapid reaction times and mild conditions make this an attractive variation of the classical 'click' reaction of azides and alkynes.

Originele taal-2English
Pagina's (van-tot)3461-3463
Aantal pagina's3
TijdschriftOrganic & Biomolecular Chemistry
Nummer van het tijdschrift19
StatusPublished - 7-okt-2008

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