Background: To describe the relationship between glycaemic control, hyperglycaemic symptoms and quality of life (HRQOL) in type 2 diabetic patients.
Methods: In a shared-care diabetes project HRQOL was assessed. A total of 1664 patients with type 2 diabetes were identified in 32 primary healthcare practices. Of these patients, 1149 were included. HRQOL was measured using a generic questionnaire (Rand-36), completed by 1006 of the 1149 participants.
Results: The number of hyperglycaemic symptoms was higher in women (1.88) compared with men (1.64), without differences in mean haemoglobin A(1c) (HbA(1c)) (7.5%). Univariate analyses showed negative relationships between all dimensions of the Rand-36 and hyperglycaemic symptoms (p <0.001), but between only one dimension and HbA(1c) (p=0.005). Multivariate analyses showed no association between any of the dimensions of the Rand-36 and HbA(1c), but the relationship between hyperglycaemic symptoms persisted in all dimensions (p <0.001). Notwithstanding these results, the presence of hyperglycaemic symptoms was related to higher HbA(1c).
Conclusion: In type 2 diabetic patients, as assessed by a generic questionnaire, there is an evident relationship between hyperglycaemic symptoms and HRQOL and not between HbA(1c) and HRQOL. Subjective hyperglycaemic symptoms are, independent of HbA(1c), important for HRQOL in type 2 diabetic patients, and should therefore not he neglected in the management of diabetes.
|Tijdschrift||Netherlands Journal of Medicine|
|Nummer van het tijdschrift||6|
|Status||Published - jun-2005|