CYTOGENETIC STUDY OF A NODULAR HYPERPLASIA OF THE THYROID AFTER IRRADIATION FOR HODGKINS-DISEASE

E VANDENBERG; JJ VANDOORMAAL; JW OOSTERHUIS; B DEJONG; J BUIST; AM VOS; A VERMEIJ; A. Dam

CYTOGENETIC STUDY OF A NODULAR HYPERPLASIA OF THE THYROID AFTER IRRADIATION FOR HODGKINS-DISEASE

E VANDENBERG^*, JJ VANDOORMAAL, JW OOSTERHUIS, B DEJONG, J BUIST, AM VOS, A VERMEIJ, A. Dam

^*Corresponding author voor dit werk

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We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.

Originele taal-2	English
Pagina's (van-tot)	15-21
Aantal pagina's	7
Tijdschrift	Cancer Genetics and Cytogenetics
Volume	53
Nummer van het tijdschrift	1
Status	Published - mei-1991

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title = "CYTOGENETIC STUDY OF A NODULAR HYPERPLASIA OF THE THYROID AFTER IRRADIATION FOR HODGKINS-DISEASE",

abstract = "We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.",

keywords = "ENDOCRINE NEOPLASIA TYPE-2A, HUMAN CHROMOSOME-3, SOLID TUMORS, CARCINOMA, CANCER, SUSCEPTIBILITY, PREDISPOSITION, INSTABILITY, ADENOMAS, ONCOGENE",

author = "E VANDENBERG and JJ VANDOORMAAL and JW OOSTERHUIS and B DEJONG and J BUIST and AM VOS and A VERMEIJ and A. Dam",

year = "1991",

month = may,

language = "English",

volume = "53",

pages = "15--21",

journal = "Cancer Genetics and Cytogenetics",

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}

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T1 - CYTOGENETIC STUDY OF A NODULAR HYPERPLASIA OF THE THYROID AFTER IRRADIATION FOR HODGKINS-DISEASE

AU - VANDENBERG, E

AU - VANDOORMAAL, JJ

AU - OOSTERHUIS, JW

AU - DEJONG, B

AU - BUIST, J

AU - VOS, AM

AU - VERMEIJ, A

AU - Dam, A.

PY - 1991/5

Y1 - 1991/5

N2 - We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.

AB - We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.

KW - ENDOCRINE NEOPLASIA TYPE-2A

KW - HUMAN CHROMOSOME-3

KW - SOLID TUMORS

KW - CARCINOMA

KW - CANCER

KW - SUSCEPTIBILITY

KW - PREDISPOSITION

KW - INSTABILITY

KW - ADENOMAS

KW - ONCOGENE

M3 - Article

SN - 0165-4608

VL - 53

SP - 15

EP - 21

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 1

ER -

CYTOGENETIC STUDY OF A NODULAR HYPERPLASIA OF THE THYROID AFTER IRRADIATION FOR HODGKINS-DISEASE

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