Detection of New Methicillin-Resistant Staphylococcus aureus Strains That Carry a Novel Genetic Homologue and Important Virulence Determinants

Artur J. Sabat, Mahir Koksal, Vika Akkerboom-Likhuta, Stefan Monecke, Andre Kriegeskorte, Ron Hendrix, Ralf Ehricht, Robin Köck, Karsten Becker, Alexander W. Friedrich*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

35 Citaten (Scopus)

Samenvatting

In this study, 18 methicillin-resistant Staphylococcus aureus (MRSA) isolates harboring staphylococcal cassette chromosome mec (SCCmec) type XI, recovered in the Dutch-German Euregio, were characterized by DNA microarrays. In contrast to previous data, we found two MRSA strains of different clonal lineages possessing SCCmec XI that carried important virulence determinants. The worrisome emergence of such toxigenic MRSA strains raises concerns that MRSA strains with enhanced virulence potential and impaired detectability by standard molecular assays may spread in Europe.

Originele taal-2English
Pagina's (van-tot)3374-3377
Aantal pagina's4
TijdschriftJournal of Clinical Microbiology
Volume50
Nummer van het tijdschrift10
DOI's
StatusPublished - okt-2012

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