Development and validation of a questionnaire-based myopia proxy in adults: the LifeLines Cohort Study

Nigus G. Asefa; Anna Neustaeter; Jelle Vehof; Ilja M. Nolte; Harold Snieder; Nomdo M. Jansonius

doi:10.1136/bjophthalmol-2021-319166

Development and validation of a questionnaire-based myopia proxy in adults: the LifeLines Cohort Study

Nigus G. Asefa^*, Anna Neustaeter, Jelle Vehof, Ilja M. Nolte, Harold Snieder, Nomdo M. Jansonius

^*Bijbehorende auteur voor dit werk

Onderzoeksoutput › Academic › peer review

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Aims To build a questionnaire-based myopia proxy and to validate the proxy by confirming its association with educational attainment and a Polygenic Risk Score (PRS) for myopia. Methods Data were collected between 2014 and 2017 from 88 646 Dutch adults from the LifeLines Cohort. First, we performed principal component analysis (PCA) to responses of five refraction-status questions. Second, we measured the refractive state in a subset of LifeLines participants (n=326) and performed logistic regression using myopia (mean spherical equivalent

Originele taal-2	English
Aantal pagina's	8
Tijdschrift	BRITISH JOURNAL OF OPHTHALMOLOGY
DOI's	https://doi.org/10.1136/bjophthalmol-2021-319166
Status	E-pub ahead of print - 10-mrt.-2022

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10.1136/bjophthalmol-2021-319166

Development and validation of a questionnaire-based myopia proxy in adultsFinal publisher's version, 1,34 MBLicentie: Taverne

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Lifelines Biobank
Bakker, S. (Creator), Dotinga, A. (Creator), Vonk, J. (Creator), Smidt, N. (Creator), Scholtens, S. (Creator), Swertz, M. (Creator), Wijmenga, C. (Creator), Wolffenbuttel, B. (Creator), Stolk, R. (Creator), van Zon, S. (Creator), Rosmalen, J. (Creator), Postma, D. S. (Creator), de Boer, R. (Creator), Navis, G. (Creator), Slaets, J. (Creator), Ormel, H. (Creator), van Dijk, F. (Creator) & Bolmer, B. (Data Manager), Lifelines, 2006
https://www.lifelines.nl/ en nog één link, https://catalogue.lifelines.nl/ (minder tonen)
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abstract = "Aims To build a questionnaire-based myopia proxy and to validate the proxy by confirming its association with educational attainment and a Polygenic Risk Score (PRS) for myopia. Methods Data were collected between 2014 and 2017 from 88 646 Dutch adults from the LifeLines Cohort. First, we performed principal component analysis (PCA) to responses of five refraction-status questions. Second, we measured the refractive state in a subset of LifeLines participants (n=326) and performed logistic regression using myopia (mean spherical equivalent",

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AU - Asefa, Nigus G.

AU - Neustaeter, Anna

AU - Vehof, Jelle

AU - Nolte, Ilja M.

AU - Snieder, Harold

AU - Jansonius, Nomdo M.

PY - 2022/3/10

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KW - optics and refraction

KW - public health

KW - epidemiology

KW - REFRACTIVE ERROR

KW - PREVALENCE

KW - POPULATION

KW - VALIDITY

KW - EUROPE

KW - AGE

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JF - BRITISH JOURNAL OF OPHTHALMOLOGY

ER -

Development and validation of a questionnaire-based myopia proxy in adults: the LifeLines Cohort Study

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Lifelines Biobank

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