De diagnostiek en behandeling van primaire hyperparathyreoïdie

W Y van der Plas, M E Noltes, A W M A Schaeffers, A H Brouwers, A N A van der Horst-Schrivers, S Kruijff

OnderzoeksoutputAcademicpeer review


- Primary hyperparathyroidism (PHPT) is characterised by elevated serum calcium levels due to elevated levels, or insufficient suppression, of parathyroid hormone (PTH).- The incidence of PHPT has increased in recent years. This is mainly the result of more frequently performed routine measurements of serum calcium, e.g. as part of postmenopausal screening.- The classically described features of PHPT - bones and stones - are not always observed and most patients are asymptomatic.- Diagnosis of PHPT is only established by biochemical testing, not by imaging.- Ultrasound and technetium-99m sestamibi SPECT-CT are the first-choice imaging modalities. These investigations are necessary to localize the parathyroid adenomas and thereby facilitate minimal invasive parathyroidectomy (MIP).

Vertaalde titel van de bijdrageDiagnostic approach and treatment of primary hyperparathyroidism
Originele taal-2Dutch
TijdschriftNederlands Tijdschrift voor Geneeskunde
Nummer van het tijdschrift0
StatusPublished - 2017

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