Diagnostic avenues in (post-transplant) lymphoproliferative disorders


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    The aim of this thesis was to investigate the role of imaging in the management of PTLD, with focus on [18F]FDG PET/CT. Additionally, we set out to explore new diagnostic methods with potential for clinical translation. In Part I (chapters 2-7), we reviewed the published literature on the role of different imaging modalities in PTLD and evaluated the diagnostic performance of [18F]FDG PET/CT for PTLD lesion detection in adults and children. Furthermore, we explored the role of [18F]FDG PET/CT semiquantification in PTLD for lesion classification and prognostication. In Part II (chapters 8-10) we proceeded to explore new avenues of research including: radiomics, identification of radiotracers adjunct to [18F]FDG and cfDNA analysis.
    Originele taal-2English
    KwalificatieDoctor of Philosophy
    Toekennende instantie
    • Rijksuniversiteit Groningen
    • Glaudemans, Andor, Supervisor
    • Dierckx, Rudi, Supervisor
    • Kwee, Thomas, Co-supervisor
    • Noordzij, Walter, Co-supervisor
    Datum van toekenning12-jan.-2022
    Plaats van publicatie[Groningen]
    StatusPublished - 2022

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