Dietary Inflammatory Potential is Associated with Poor Periodontal Health: A Population-based Study

An Li*, Yuntao Chen, Annemarie A Schuller, Luc W M van der Sluis, Geerten-Has E Tjakkes

*Bijbehorende auteur voor dit werk

    OnderzoeksoutputAcademicpeer review

    14 Citaten (Scopus)
    54 Downloads (Pure)


    AIM: To investigate the association between dietary inflammatory potential and poor periodontal health.

    MATERIAL AND METHODS: A cross-sectional analysis of a nationally representative sample of participants was performed. NHANES 2011-2014 (n = 7,081) and NHANES 2001-2004 (n = 5,098) were used as discovery and validation datasets, respectively. The energy-adjusted dietary inflammatory index (E-DII) score was calculated for each participant based on 24-hr dietary recalls to assess diet-associated inflammation. Periodontitis was defined by the CDC/AAP using clinical periodontal parameters. Natural cubic spline was applied to identify any non-linear associations of the E-DII score with moderate/severe periodontitis. Furthermore, interaction analyses were performed by age, gender, and race/ethnicity to explore the moderating roles of these factors.

    RESULTS: In the discovery dataset, a non-linear positive relationship with periodontitis was identified for the E-DII score (P non-linearity < .001) after adjustment for potential confounders. Compared with those individuals in the lowest tertile of E-DII, participants in the highest tertile who consumed a pro-inflammatory diet were 53% more likely to be periodontitis (OR tertile3vs1 = 1.53, 95% CI: 1.33-1.77). The validation dataset showed similar associations. Relatively stronger associations were seen in older adults and males.

    CONCLUSION: Consuming a pro-inflammatory diet indicated by the E-DII score is associated with periodontal disease in the U.S. general adult population.

    Originele taal-2English
    Pagina's (van-tot)907-918
    Aantal pagina's12
    TijdschriftJournal of Clinical Periodontology
    Nummer van het tijdschrift7
    Vroegere onlinedatum25-apr.-2021
    StatusPublished - jul.-2021

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