Diffusion tensor imaging and magnetic resonance spectroscopy of the brain in a patient with Sturge-Weber syndrome

P. E. Sijens*, E. W. Gieteling, L. C. Meiners, D. A. Sival, J. H. Potze, R. Irwan, M. Oudkerk

*Bijbehorende auteur voor dit werk

    OnderzoeksoutputAcademicpeer review

    4 Citaten (Scopus)


    Quantitative brain MR spectroscopy (MRS) and diffusion tensor imaging (DTI) were used to characterize one patient with Sturge-Weber syndrome. Choline increases and N-acetylaspartate decreases were observed in pathologic frontal gray matter tissue compared to contralateral unaffected brain tissue without any change in the diffusion tensor imaging parameters (fractional anisotropy, apparent diffusion coefficient). The N-acetylaspartate decreases and/or choline increases observed here and in eight previously described Sturge-Weber patients probably reflect neuronal loss or dysfunction and demyelination as a result of recurrent seizures.

    Originele taal-2English
    Pagina's (van-tot)972-976
    Aantal pagina's5
    TijdschriftActa Radiologica
    Nummer van het tijdschrift9
    StatusPublished - nov.-2006

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