Discovery of Inhibitors by Combinatorial-Chemistry Approaches

Ramon van der Vlag

Onderzoeksoutput: Thesis fully internal (DIV)

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Samenvatting

This thesis describes our efforts to develop inhibitors using combinatorial-chemistry approaches. These approaches can potentially speed-up the drug discovery trajectory and the discovered molecules could be used as starting points for future drug development projects targeting 15-LOX-1, MIF and/or MDM2. The aforementioned targets are all proteins that play an important role in common diseases.
Originele taal-2English
KwalificatieDoctor of Philosophy
Toekennende instantie
  • Rijksuniversiteit Groningen
Begeleider(s)/adviseur
  • Hirsch, Anna, Supervisor
  • Dekker, Frank, Supervisor
Datum van toekenning27-nov-2020
Plaats van publicatie[Groningen]
Uitgever
DOI's
StatusPublished - 2020

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