Does cancer cell-expressed SLAMF7 impact on CD47-mediated phagocytosis?

Renee Bouwstra*, Tom van Meerten, Edwin Bremer

*Bijbehorende auteur voor dit werk

Onderzoeksoutput: Comment/Letter to the editorAcademicpeer review

4 Citaten (Scopus)
2 Downloads (Pure)

Samenvatting

Innate immune checkpoint CD47 has emerged as a prominent target for cancer immunotherapy and defining biomarkers predictive of response will be a crucial step towards clinical implementation. Hereto, we investigated the importance of a previously reported requisite for SLAM family member 7(SLAMF7) expression on cancer cell phagocytosis for effective CD47 antibody therapy.

Originele taal-2English
Artikelnummer1600349
Aantal pagina's3
TijdschriftMolecular and Cellular Oncology
Volume6
Nummer van het tijdschrift3
DOI's
StatusPublished - 1-jan.-2019

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