ECNP consensus meeting. Bipolar depression. Nice, March 2007

Guy M. Goodwin*, Ian Anderson, Celso Arango, Charles L. Bowden, Chantal Henry, Philip B. Mitchell, Willem A. Nolen, Eduard Vieta, Hans-Ulrich Wittchen

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

135 Citaten (Scopus)


Diagnosis and epidemiology: DSM-IV, specifically its text revision DSM-IV-TR, remains the preferred diagnostic system. When employed in general population samples, prevalence estimates of bipolar disorder are relatively consistent across studies in Europe and USA. In community studies, first onset of bipolar mood disorder is usually in the mid-teenage years and twenties, and the occurrence of a major depressive episode or hypomania is usually its first manifestation. Since reliable criteria for delineating unipolar (UP) and bipolar (BP) depression cross-sectionally are currently lacking, there is a longitudinal risk - probably over 10% - that initial UP patients ultimately turn out as BP in the longer run. Its early onset implies a severe potential burden of disease in terms of impaired social and neuropsychological development,most of which is attributable to depression.

Originele taal-2English
Pagina's (van-tot)535-549
Aantal pagina's15
TijdschriftEuropean Neuropsychopharmacology
Nummer van het tijdschrift7
StatusPublished - jul-2008

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