Economic evaluations of hepatitis A vaccination in middle-income countries

Auliya A Suwantika, Selen Yegenoglu, Arthorn Riewpaiboon, Hong-Anh T Tu, Maarten J Postma

    OnderzoeksoutputAcademicpeer review

    15 Citaten (Scopus)


    Economic evaluations of hepatitis A vaccination are important to assist national and international policy makers in different jurisdictions on making effective decisions. Up to now, a comprehensive review of the potential health and economic benefits on hepatitis A vaccination in middle-income countries (MICs) has not been performed yet. In this study, we reviewed the literature on the cost-effectiveness of hepatitis A vaccination in MICs. Most of the studies confirmed that hepatitis A vaccination was cost effective or even cost saving under certain conditions. We found that vaccine price, medical costs, incidence and discount rate were the most influential parameters on the sensitivity analyses. Vaccine price has been shown as a barrier for MICs in implementing universal vaccination of hepatitis A. Given their relatively limited financial resources, implementation of single-dose vaccination could be considered. Despite our findings, we argue that further economic evaluations in MICs are still required in the near future.

    Originele taal-2English
    Pagina's (van-tot)1479-1494
    Aantal pagina's16
    TijdschriftExpert review of vaccines
    Nummer van het tijdschrift12
    StatusPublished - dec.-2013

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