Een letale blaarvormende auto-immuunziekte

M. Aniek Lamberts*, G. F.H. Diercks, K. de Leeuw, J. M. Meijer

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

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Samenvatting

Dermatomyositis is an autoimmune disease characterized by chronic inflammation of skin and muscle. Anti-melanoma differentiation-associated gene 5 (MDA5) associated dermatomyositis is a recently described variant that displays a unique dermatological phenotype consisting of punched-out cutaneous ulcers, palmar erythema, papules or blisters at typical sites of dermatomyositis. Moreover, anti-MDA5 associated dermatomyositis patients have an increased risk to develop a rapidly progressive interstitial lung disease with a potentially fatal course. Cutaneous ulcers are an important predictor for the development of interstitial lung disease. We report an illustrative case of anti-MDA5 associated dermatomyositis.

Vertaalde titel van de bijdrageA lethal blistering autoimmune disease
Originele taal-2Dutch
Pagina's (van-tot)36-38
Aantal pagina's3
TijdschriftNederlands Tijdschrift voor Dermatologie en Venereologie
Volume31
Nummer van het tijdschrift6
StatusPublished - jun.-2021

Keywords

  • autoimmune disease-systemic disease
  • blisters-MDA-5-melanoma-differentiaton-associated gene 5
  • dermatomyositis-interstitial lung disease

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