Effect of Systolic Blood Pressure on Left Ventricular Structure and Function A Mendelian Randomization Study

Tom Hendriks, M. Abdullah Said, Lara M. A. Janssen, M. Yldau van der Ende, Dirk J. van Veldhuisen, Niek Verweij, Pim van der Harst*

*Corresponding author voor dit werk

OnderzoeksoutputAcademicpeer review

28 Citaten (Scopus)
250 Downloads (Pure)

Samenvatting

We aimed to estimate the effects of a lifelong exposure to high systolic blood pressure (SBP) on left ventricular (LV) structure and function using Mendelian randomization. A total of 5596 participants of the UK Biobank were included for whom cardiovascular magnetic resonance imaging and genetic data were available. Major exclusion criteria included nonwhite ethnicity, major cardiovascular disease, and body mass index >30 or

Originele taal-2English
Pagina's (van-tot)826-832
Aantal pagina's7
TijdschriftHypertension
Volume74
Nummer van het tijdschrift4
DOI's
StatusPublished - okt.-2019

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