TY - JOUR
T1 - Effects of divorce on Dutch boys' and girls' externalizing behavior in Gene x Environment perspective
T2 - Diathesis stress or differential susceptibility in the Dutch Tracking Adolescents' Individual Lives Survey study?
AU - Nederhof, Esther
AU - Belsky, Jay
AU - Ormel, Johan
AU - Oldehinkel, Albertine J.
PY - 2012/8
Y1 - 2012/8
N2 - The effects of divorce on children's behavioral development have proven to be quite varied across studies, and most developmental and family scholars today appreciate the great heterogeneity in divorce effects. Thus, this inquiry sought to determine whether select dopaminergic genes previously associated with externalizing behavior and/or found to moderate diverse environmental effects (dopamine receptors D2 and D4, catechol-O-methyltransferase) might moderate divorce effects on adolescent self-reported externalizing problems; and, if so, whether evidence of gene environment (G x E) interaction would prove consistent with diathesis stress or differential-susceptibility models of environmental action. Data from the first and third wave of the Dutch Tracking Adolescents' Individual Lives Survey (n = 1,134) revealed some evidence of G x E interaction reflecting diathesis stress but not differential susceptibility. It is intriguing that some evidence pointed to "vantage sensitivity," which are benefits accruing to those with a specific genotype when their parents remained together, the exact opposite of diathesis stress. The limits of this work are considered, especially with regard to the conditions for testing differential susceptibility, and future directions are outlined.
AB - The effects of divorce on children's behavioral development have proven to be quite varied across studies, and most developmental and family scholars today appreciate the great heterogeneity in divorce effects. Thus, this inquiry sought to determine whether select dopaminergic genes previously associated with externalizing behavior and/or found to moderate diverse environmental effects (dopamine receptors D2 and D4, catechol-O-methyltransferase) might moderate divorce effects on adolescent self-reported externalizing problems; and, if so, whether evidence of gene environment (G x E) interaction would prove consistent with diathesis stress or differential-susceptibility models of environmental action. Data from the first and third wave of the Dutch Tracking Adolescents' Individual Lives Survey (n = 1,134) revealed some evidence of G x E interaction reflecting diathesis stress but not differential susceptibility. It is intriguing that some evidence pointed to "vantage sensitivity," which are benefits accruing to those with a specific genotype when their parents remained together, the exact opposite of diathesis stress. The limits of this work are considered, especially with regard to the conditions for testing differential susceptibility, and future directions are outlined.
KW - CATECHOL-O-METHYLTRANSFERASE
KW - FAMILY-STRUCTURE TRANSITIONS
KW - PARENTAL DIVORCE
KW - CHILDRENS ADJUSTMENT
KW - MARITAL INSTABILITY
KW - MENTAL-HEALTH
KW - OFFSPRING PSYCHOPATHOLOGY
KW - SEROTONIN TRANSPORTER
KW - LIFE
KW - EXPERIENCE
U2 - 10.1017/S0954579412000454
DO - 10.1017/S0954579412000454
M3 - Article
SN - 0954-5794
VL - 24
SP - 929
EP - 939
JO - Development and Psychopathology
JF - Development and Psychopathology
IS - 3
ER -