Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method for amino acid esters and primary amines

Ben L. Feringa; Bert Strijtveen; Richard M. Kellogg

doi:10.1021/jo00376a100

Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method for amino acid esters and primary amines

Ben L. Feringa^*, Bert Strijtveen, Richard M. Kellogg

^*Corresponding author voor dit werk

Onderzoeksoutput › Academic › peer review

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Amino acid esters and primary amines yield diastereoisomeric methylphosphonic diamides 5 upon reaction with MePSCl2. The enantiomeric excess of amino acid esters and amines is easily determined by measurement of the ratio of diastereoisomers of 5 by 31P NMR spectroscopy.

Originele taal-2	English
Pagina's (van-tot)	5484-5486
Aantal pagina's	3
Tijdschrift	The Journal of Organic Chemistry
Volume	51
Nummer van het tijdschrift	26
DOI's	https://doi.org/10.1021/jo00376a100
Status	Published - 26-dec.-1986

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Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method
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title = "Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method for amino acid esters and primary amines",

abstract = "Amino acid esters and primary amines yield diastereoisomeric methylphosphonic diamides 5 upon reaction with MePSCl2. The enantiomeric excess of amino acid esters and amines is easily determined by measurement of the ratio of diastereoisomers of 5 by 31P NMR spectroscopy.",

author = "Feringa, \{Ben L.\} and Bert Strijtveen and Kellogg, \{Richard M.\}",

note = "Relation: http://www.rug.nl/scheikunde/ date\_submitted:2005 Rights: University of Groningen. Stratingh Institute",

year = "1986",

month = dec,

day = "26",

doi = "10.1021/jo00376a100",

language = "English",

volume = "51",

pages = "5484--5486",

journal = "The Journal of Organic Chemistry",

issn = "1520-6904",

publisher = "AMER CHEMICAL SOC INC",

number = "26",

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TY - JOUR

T1 - Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method for amino acid esters and primary amines

AU - Feringa, Ben L.

AU - Strijtveen, Bert

AU - Kellogg, Richard M.

N1 - Relation: http://www.rug.nl/scheikunde/ date_submitted:2005 Rights: University of Groningen. Stratingh Institute

PY - 1986/12/26

Y1 - 1986/12/26

N2 - Amino acid esters and primary amines yield diastereoisomeric methylphosphonic diamides 5 upon reaction with MePSCl2. The enantiomeric excess of amino acid esters and amines is easily determined by measurement of the ratio of diastereoisomers of 5 by 31P NMR spectroscopy.

AB - Amino acid esters and primary amines yield diastereoisomeric methylphosphonic diamides 5 upon reaction with MePSCl2. The enantiomeric excess of amino acid esters and amines is easily determined by measurement of the ratio of diastereoisomers of 5 by 31P NMR spectroscopy.

U2 - 10.1021/jo00376a100

DO - 10.1021/jo00376a100

M3 - Letter

SN - 1520-6904

VL - 51

SP - 5484

EP - 5486

JO - The Journal of Organic Chemistry

JF - The Journal of Organic Chemistry

IS - 26

ER -

Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method for amino acid esters and primary amines

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