Enhancing the antimicrobial potential of lanthipeptides by employing different engineering strategies

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The research described in this thesis aimed to develop novel approaches to engineer lantibiotics, to control either planktonic pathogens or biofilm-infections. To expand the toolbox of engineering lantibiotics, this thesis furthermore aimed at generating a method for obtaining lanthipeptide synthetases with adapted substrate specificity by directed evolution.
Originele taal-2English
KwalificatieDoctor of Philosophy
Toekennende instantie
  • Rijksuniversiteit Groningen
Begeleider(s)/adviseur
  • Kuipers, Oscar, Supervisor
  • Moll, Gert, Supervisor
Datum van toekenning22-jun-2020
Plaats van publicatie[Groningen]
Uitgever
Gedrukte ISBN's9789403427836
Elektronische ISBN's9789403427843
DOI's
StatusPublished - 2020

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