Samenvatting
Background: Our ability to accurately predict development and outcome of early expression of psychosis is limited. To elucidate the
mechanisms underlying psychopathology, a broader, transdiagnostic approach that acknowledges the complexity of mental illness is required. The application of the novel network paradigm may be fruitful here.
Methods: We explore the applicability of a transdiagnostic network approach to psychosis. Data pertain to the third wave (second followup)
of a sample of adolescents originally recruited at age 7–8 years (the PSYCHE study). At baseline, N = 347 children with auditory verbal hallucinations (AVH) as well as N = 347 control children were included. N = 293 of these N = 694 children participated in the second follow-up (mean age 18.9 years; 59% women). Participants completed the Community Assessment of Psychic Experiences (CAPE) and the Depression, Anxiety and Stress Scale (DASS-21). A specific type of network model, the Ising model, was applied to dichotomized CAPE
and DASS items.
Results: Our results show that it is possible to map the multidimensional experiences of the CAPE and the DASS as a network, and that examination of interconnectedness of
experiences provides information that cannot be easily distilled from composite scores,
e.g. correlations of sum scores. Interconnections of experiences within the same domain were observed, as well as interconnections between
experiences of multiple psychopathological domains.
mechanisms underlying psychopathology, a broader, transdiagnostic approach that acknowledges the complexity of mental illness is required. The application of the novel network paradigm may be fruitful here.
Methods: We explore the applicability of a transdiagnostic network approach to psychosis. Data pertain to the third wave (second followup)
of a sample of adolescents originally recruited at age 7–8 years (the PSYCHE study). At baseline, N = 347 children with auditory verbal hallucinations (AVH) as well as N = 347 control children were included. N = 293 of these N = 694 children participated in the second follow-up (mean age 18.9 years; 59% women). Participants completed the Community Assessment of Psychic Experiences (CAPE) and the Depression, Anxiety and Stress Scale (DASS-21). A specific type of network model, the Ising model, was applied to dichotomized CAPE
and DASS items.
Results: Our results show that it is possible to map the multidimensional experiences of the CAPE and the DASS as a network, and that examination of interconnectedness of
experiences provides information that cannot be easily distilled from composite scores,
e.g. correlations of sum scores. Interconnections of experiences within the same domain were observed, as well as interconnections between
experiences of multiple psychopathological domains.
Originele taal-2 | English |
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Pagina's | 16010 |
Aantal pagina's | 16010 |
Status | Published - 2016 |
Evenement | Schizophrenia International Research Society, SIRS, 2016 - Florence, Italy Duur: 2-apr.-2016 → 6-apr.-2016 |
Conference
Conference | Schizophrenia International Research Society, SIRS, 2016 |
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Land/Regio | Italy |
Stad | Florence |
Periode | 02/04/2016 → 06/04/2016 |