Factors Associated With Mortality in Low-Risk Pediatric Critical Care Patients in The Netherlands

Carin W. Verlaat*, Idse H. Visser, Nina Wubben, Jan A. Hazelzet, Joris Lemson, Dick van Waardenburg, Douwe van der Heide, Nicolette A. van Dam, Nicolaas J. Jansen, Mark van Heerde, Cynthia van der Starre, Roelie van Asperen, Martin Kneyber, Job B. van Woensel, Mark van den Boogaard, Johannes van der Hoeven, SKIC Dutch Collaborative PICU Res

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

10 Citaten (Scopus)

Samenvatting

Objective: To determine differences between survivors and non-survivors and factors associated with mortality in pediatric intensive care patients with low risk of mortality.

Design: Retrospective cohort study.

Setting: Patients were selected from a national database including all admissions to the PICUs in The Netherlands between 2006 and 2012.

Patients: Patients less than 18 years old admitted to the PICU with a predicted mortality risk lower than 1% according to either the recalibrated Pediatric Risk of Mortality or the Pediatric Index of Mortality 2 were included.

Interventions: None.

Measurements and Main Results: In total, 16,874 low-risk admissions were included of which 86 patients (0.5%) died. Nonsurvivors had more unplanned admissions (74.4% vs 38.5%; p <0.001), had more complex chronic conditions (76.7% vs 58.8%; p = 0.001), were more often mechanically ventilated (88.1% vs 34.9%; p <0.001), and had a longer length of stay (median, 11 [interquartile range, 5-32] d vs median, 3 [interquartile range, 2-5] d; p <0.001) when compared with survivors. Factors significantly associated with mortality were complex chronic conditions (odds ratio, 3.29; 95% CI, 1.97-5.50), unplanned admissions (odds ratio, 5.78; 95% CI, 3.40-9.81), and admissions in spring/summer (odds ratio, 1.67; 95% CI, 1.08-2.58).

Conclusions: Nonsurvivors in the PICU with a low predicted mortality risk have recognizable risk factors including complex chronic condition and unplanned admissions.

Originele taal-2English
Pagina's (van-tot)E155-E161
Aantal pagina's7
TijdschriftPediatric critical care medicine
Volume18
Nummer van het tijdschrift4
DOI's
StatusPublished - 1-apr-2017

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