Feasibility and accuracy of tissue characterization with dual source computed tomography

Joanne K. Van Abbema, Arjen Van der Schaaf, Wisnu Kristanto, Jaap M. Groen, Marcel J. W. Greuter*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

15 Citaten (Scopus)


PURPOSE: To evaluate the feasibility and accuracy of a model for tissue characterization with dual source computed tomography (DSCT).

METHODS AND MATERIALS: A model for tissue characterization in CT was used with a parameterization of linear attenuation coefficients. Sixteen chemical substances with effective atomic numbers between 5.21 and 13.08 and electron densities between 2.20 and 4.12 x10(23) electrons/cm(3) were scanned at energies of 80 and 140 kV on a DSCT. From the reconstructed dual energy data sets, effective atomic numbers and electron densities of the substances were calculated.

RESULTS: Our presented model using DSCT approximated the effective atomic numbers and effective electron densities of 16 substances very well. The measured effective atomic numbers deviated 3.4 ± 6.8% (R(2) = 0.994) from theoretical effective atomic numbers. In addition, measured effective electron densities deviated -0.6 ± 2.2% (R(2) = 0.999) from theoretical effective electron densities.

CONCLUSION: Effective atomic numbers and effective electron densities can be determined with a high accuracy with DSCT. Therefore the model can be of potential benefit for clinical applications of quantitative tissue characterization with DSCT.

Originele taal-2English
Pagina's (van-tot)25-32
Aantal pagina's8
TijdschriftPhysica medica-European journal of medical physics
Nummer van het tijdschrift1
StatusPublished - jan-2012

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