FIRST-TRIMESTER PRENATAL-DIAGNOSIS IN TWIN PREGNANCIES

GCML CHRISTIAENS*, JC Oosterwijk, RH STIGTER, PP DEUTZTERLOUW, ALJ KNEPPERS, E BAKKER

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

6 Citaten (Scopus)

Samenvatting

Two twin pregnancies at risk for a sex-linked disorder are described. Both pregnancies were dichorionic. Transabdominal sampling was chosen for prenatal diagnosis. Molecular genetic techniques raised suspicion with regard to the accuracy of the samples in one case. Second-trimester amniocentesis confirmed the error. Selective feticide of the affected fetus was performed. When first-trimester prenatal diagnosis is offered in dichorionic twin pregnancies, confirmation through molecular genetic testing can confirm that villi have been obtained from different fetuses. All parties must be aware that additional invasive diagnostic procedures in the second trimester may be required in cases of doubt.

Originele taal-2English
Pagina's (van-tot)51-55
Aantal pagina's5
TijdschriftPrenatal Diagnosis
Volume14
Nummer van het tijdschrift1
StatusPublished - jan-1994

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