Flavivirus cell entry and membrane fusion

Jolanda M. Smit; Bastiaan Moesker; Izabela Rodenhuis-Zybert; Jan Wilschut

doi:10.3390/v3020160

Flavivirus cell entry and membrane fusion

Jolanda M. Smit^*, Bastiaan Moesker, Izabela Rodenhuis-Zybert, Jan Wilschut

^*Corresponding author voor dit werk

Microbes in Health and Disease (MHD)

Onderzoeksoutput: Editorial › Academic › peer review

237 Citaten (Scopus)

406 Downloads (Pure)

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Flaviviruses, such as dengue virus and West Nile virus, are enveloped viruses that infect cells through receptor-mediated endocytosis and fusion from within acidic endosomes. The cell entry process of flaviviruses is mediated by the viral E glycoprotein. This short review will address recent advances in the understanding of flavivirus cell entry with specific emphasis on the recent study of Zaitseva and coworkers, indicating that anionic lipids might play a crucial role in the fusion process of dengue virus [1].

Originele taal-2	English
Pagina's (van-tot)	160-171
Aantal pagina's	12
Tijdschrift	Viruses
Volume	3
Nummer van het tijdschrift	2
DOI's	https://doi.org/10.3390/v3020160
Status	Published - 22-feb.-2011

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10.3390/v3020160Licentie: CC BY-NC-SA

Flavivirus Cell Entry and Membrane FusionFinal publisher's version, 188 KBLicentie: CC BY-NC-SA

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title = "Flavivirus cell entry and membrane fusion",

abstract = "Flaviviruses, such as dengue virus and West Nile virus, are enveloped viruses that infect cells through receptor-mediated endocytosis and fusion from within acidic endosomes. The cell entry process of flaviviruses is mediated by the viral E glycoprotein. This short review will address recent advances in the understanding of flavivirus cell entry with specific emphasis on the recent study of Zaitseva and coworkers, indicating that anionic lipids might play a crucial role in the fusion process of dengue virus [1].",

keywords = "flavivirus, membrane fusion, anionic lipids, negatively charged lipids, cell entry, receptor, dengue, West Nile virus, WEST-NILE-VIRUS, BORNE ENCEPHALITIS-VIRUS, YELLOW-FEVER VIRUS, HUMAN DENDRITIC CELLS, PH-DEPENDENT FUSION, DENGUE-VIRUS, HEPARAN-SULFATE, INFLUENZA-VIRUS, DC-SIGN, ENVELOPE PROTEIN",

author = "Smit, {Jolanda M.} and Bastiaan Moesker and Izabela Rodenhuis-Zybert and Jan Wilschut",

year = "2011",

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T1 - Flavivirus cell entry and membrane fusion

AU - Smit, Jolanda M.

AU - Moesker, Bastiaan

AU - Rodenhuis-Zybert, Izabela

AU - Wilschut, Jan

PY - 2011/2/22

Y1 - 2011/2/22

N2 - Flaviviruses, such as dengue virus and West Nile virus, are enveloped viruses that infect cells through receptor-mediated endocytosis and fusion from within acidic endosomes. The cell entry process of flaviviruses is mediated by the viral E glycoprotein. This short review will address recent advances in the understanding of flavivirus cell entry with specific emphasis on the recent study of Zaitseva and coworkers, indicating that anionic lipids might play a crucial role in the fusion process of dengue virus [1].

AB - Flaviviruses, such as dengue virus and West Nile virus, are enveloped viruses that infect cells through receptor-mediated endocytosis and fusion from within acidic endosomes. The cell entry process of flaviviruses is mediated by the viral E glycoprotein. This short review will address recent advances in the understanding of flavivirus cell entry with specific emphasis on the recent study of Zaitseva and coworkers, indicating that anionic lipids might play a crucial role in the fusion process of dengue virus [1].

KW - flavivirus

KW - membrane fusion

KW - anionic lipids

KW - negatively charged lipids

KW - cell entry

KW - receptor

KW - dengue

KW - West Nile virus

KW - WEST-NILE-VIRUS

KW - BORNE ENCEPHALITIS-VIRUS

KW - YELLOW-FEVER VIRUS

KW - HUMAN DENDRITIC CELLS

KW - PH-DEPENDENT FUSION

KW - DENGUE-VIRUS

KW - HEPARAN-SULFATE

KW - INFLUENZA-VIRUS

KW - DC-SIGN

KW - ENVELOPE PROTEIN

U2 - 10.3390/v3020160

DO - 10.3390/v3020160

M3 - Editorial

C2 - 22049308

SN - 1999-4915

VL - 3

SP - 160

EP - 171

JO - Viruses

JF - Viruses

IS - 2

ER -

Flavivirus cell entry and membrane fusion

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