Flavivirus cell entry and membrane fusion

Jolanda M. Smit*, Bastiaan Moesker, Izabela Rodenhuis-Zybert, Jan Wilschut

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

171 Citaten (Scopus)
285 Downloads (Pure)

Samenvatting

Flaviviruses, such as dengue virus and West Nile virus, are enveloped viruses that infect cells through receptor-mediated endocytosis and fusion from within acidic endosomes. The cell entry process of flaviviruses is mediated by the viral E glycoprotein. This short review will address recent advances in the understanding of flavivirus cell entry with specific emphasis on the recent study of Zaitseva and coworkers, indicating that anionic lipids might play a crucial role in the fusion process of dengue virus [1].

Originele taal-2English
Pagina's (van-tot)160-171
Aantal pagina's12
TijdschriftViruses
Volume3
Nummer van het tijdschrift2
DOI's
StatusPublished - 22-feb-2011

Citeer dit