Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

Johan M. S. van der Schoot; Felix L. Fennemann; Michael Valente; Yusuf Dolen; Iris M. Hagemans; Anouk M. D. Becker; Camille M. Le Gall; Duco van Dalen; Alper Cevirgel; Jaco A. C. van Bruggen; Melanie Engelfriet; Tomislav Caval; Arthur E. H. Bentlage; Marieke F. Fransen; Maaike Nederend; Jeanette H. W. Leusen; Albert J. R. Heck; Gestur Vidarsson; Carl G. Figdor; Martijn Verdoes; Ferenc A. Scheeren

doi:10.1126/sciadv.aaw1822

Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

Johan M. S. van der Schoot, Felix L. Fennemann, Michael Valente, Yusuf Dolen, Iris M. Hagemans, Anouk M. D. Becker, Camille M. Le Gall, Duco van Dalen, Alper Cevirgel, Jaco A. C. van Bruggen, Melanie Engelfriet, Tomislav Caval, Arthur E. H. Bentlage, Marieke F. Fransen, Maaike Nederend, Jeanette H. W. Leusen, Albert J. R. Heck, Gestur Vidarsson, Carl G. Figdor, Martijn VerdoesFerenc A. Scheeren

Onderzoeksoutput: Article › Academic › peer review

16 Citaten (Scopus)

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Originele taal-2	English
Artikelnummer	eaaw1822
Aantal pagina's	12
Tijdschrift	Science Advances
Volume	5
Nummer van het tijdschrift	8
DOI's	https://doi.org/10.1126/sciadv.aaw1822
Status	Published - 2-aug.-2019
Extern gepubliceerd	Ja

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Schoot, J. M. S. V. D., Fennemann, F. L., Valente, M., Dolen, Y., Hagemans, I. M., Becker, A. M. D., Gall, C. M. L., Dalen, D. V., Cevirgel, A., Bruggen, J. A. C. V., Engelfriet, M., Caval, T., Bentlage, A. E. H., Fransen, M. F., Nederend, M., Leusen, J. H. W., Heck, A. J. R., Vidarsson, G., Figdor, C. G., ... Scheeren, F. A. (2019). Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering. Science Advances, 5(8), Artikel eaaw1822. https://doi.org/10.1126/sciadv.aaw1822

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title = "Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering",

author = "Schoot, {Johan M. S. van der} and Fennemann, {Felix L.} and Michael Valente and Yusuf Dolen and Hagemans, {Iris M.} and Becker, {Anouk M. D.} and Gall, {Camille M. Le} and Dalen, {Duco van} and Alper Cevirgel and Bruggen, {Jaco A. C. van} and Melanie Engelfriet and Tomislav Caval and Bentlage, {Arthur E. H.} and Fransen, {Marieke F.} and Maaike Nederend and Leusen, {Jeanette H. W.} and Heck, {Albert J. R.} and Gestur Vidarsson and Figdor, {Carl G.} and Martijn Verdoes and Scheeren, {Ferenc A.}",

year = "2019",

month = aug,

day = "2",

doi = "10.1126/sciadv.aaw1822",

language = "English",

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Schoot, JMSVD, Fennemann, FL, Valente, M, Dolen, Y, Hagemans, IM, Becker, AMD, Gall, CML, Dalen, DV, Cevirgel, A, Bruggen, JACV, Engelfriet, M, Caval, T, Bentlage, AEH, Fransen, MF, Nederend, M, Leusen, JHW, Heck, AJR, Vidarsson, G, Figdor, CG, Verdoes, M & Scheeren, FA 2019, 'Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering', Science Advances, vol. 5, nr. 8, eaaw1822. https://doi.org/10.1126/sciadv.aaw1822

TY - JOUR

T1 - Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

AU - Schoot, Johan M. S. van der

AU - Fennemann, Felix L.

AU - Valente, Michael

AU - Dolen, Yusuf

AU - Hagemans, Iris M.

AU - Becker, Anouk M. D.

AU - Gall, Camille M. Le

AU - Dalen, Duco van

AU - Cevirgel, Alper

AU - Bruggen, Jaco A. C. van

AU - Engelfriet, Melanie

AU - Caval, Tomislav

AU - Bentlage, Arthur E. H.

AU - Fransen, Marieke F.

AU - Nederend, Maaike

AU - Leusen, Jeanette H. W.

AU - Heck, Albert J. R.

AU - Vidarsson, Gestur

AU - Figdor, Carl G.

AU - Verdoes, Martijn

AU - Scheeren, Ferenc A.

PY - 2019/8/2

Y1 - 2019/8/2

U2 - 10.1126/sciadv.aaw1822

DO - 10.1126/sciadv.aaw1822

M3 - Article

SN - 2375-2548

VL - 5

JO - Science Advances

JF - Science Advances

IS - 8

M1 - eaaw1822

ER -