Functionality of Sortase A in Lactococcus lactis

Yakhya Dieye; Virginie Oxaran; Florence Ledue-Clier; Walid Alkhalaf; Girbe Buist; Vincent Juillard; Chang Won Lee; Jean-Christophe Piard

doi:10.1128/AEM.00928-10

Functionality of Sortase A in Lactococcus lactis

Yakhya Dieye, Virginie Oxaran, Florence Ledue-Clier, Walid Alkhalaf, Girbe Buist, Vincent Juillard, Chang Won Lee, Jean-Christophe Piard^*

^*Corresponding author voor dit werk

Moleculaire Genetica

Onderzoeksoutput: Article › Academic › peer review

37 Citaten (Scopus)

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Lactococcus lactis IL1403 harbors a putative sortase A (SrtA) and 11 putative sortase substrates that carry the canonical LPXTG signature of such substrates. We report here on the functionality of SrtA to anchor five LPXTG substrates to the cell wall, thus suggesting that SrtA is the housekeeping sortase in L. lactis IL1403.

Originele taal-2	English
Pagina's (van-tot)	7332-7337
Aantal pagina's	6
Tijdschrift	Applied and environmental microbiology
Volume	76
Nummer van het tijdschrift	21
DOI's	https://doi.org/10.1128/AEM.00928-10
Status	Published - nov.-2010

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Functionality of Sortase A in Lactococcus lactis
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title = "Functionality of Sortase A in Lactococcus lactis",

abstract = "Lactococcus lactis IL1403 harbors a putative sortase A (SrtA) and 11 putative sortase substrates that carry the canonical LPXTG signature of such substrates. We report here on the functionality of SrtA to anchor five LPXTG substrates to the cell wall, thus suggesting that SrtA is the housekeeping sortase in L. lactis IL1403.",

keywords = "GRAM-POSITIVE BACTERIA, CELL-WALL, STREPTOCOCCUS-PYOGENES, SURFACE-PROTEINS, ACID BACTERIA, BACILLUS-SUBTILIS, BINDING DOMAIN, SUBSP LACTIS, E7 ANTIGEN, GENE",

author = "Yakhya Dieye and Virginie Oxaran and Florence Ledue-Clier and Walid Alkhalaf and Girbe Buist and Vincent Juillard and Lee, {Chang Won} and Jean-Christophe Piard",

year = "2010",

month = nov,

doi = "10.1128/AEM.00928-10",

language = "English",

volume = "76",

pages = "7332--7337",

journal = "Applied and environmental microbiology",

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TY - JOUR

T1 - Functionality of Sortase A in Lactococcus lactis

AU - Dieye, Yakhya

AU - Oxaran, Virginie

AU - Ledue-Clier, Florence

AU - Alkhalaf, Walid

AU - Buist, Girbe

AU - Juillard, Vincent

AU - Lee, Chang Won

AU - Piard, Jean-Christophe

PY - 2010/11

Y1 - 2010/11

N2 - Lactococcus lactis IL1403 harbors a putative sortase A (SrtA) and 11 putative sortase substrates that carry the canonical LPXTG signature of such substrates. We report here on the functionality of SrtA to anchor five LPXTG substrates to the cell wall, thus suggesting that SrtA is the housekeeping sortase in L. lactis IL1403.

AB - Lactococcus lactis IL1403 harbors a putative sortase A (SrtA) and 11 putative sortase substrates that carry the canonical LPXTG signature of such substrates. We report here on the functionality of SrtA to anchor five LPXTG substrates to the cell wall, thus suggesting that SrtA is the housekeeping sortase in L. lactis IL1403.

KW - GRAM-POSITIVE BACTERIA

KW - CELL-WALL

KW - STREPTOCOCCUS-PYOGENES

KW - SURFACE-PROTEINS

KW - ACID BACTERIA

KW - BACILLUS-SUBTILIS

KW - BINDING DOMAIN

KW - SUBSP LACTIS

KW - E7 ANTIGEN

KW - GENE

U2 - 10.1128/AEM.00928-10

DO - 10.1128/AEM.00928-10

M3 - Article

SN - 0099-2240

VL - 76

SP - 7332

EP - 7337

JO - Applied and environmental microbiology

JF - Applied and environmental microbiology

IS - 21

ER -

Functionality of Sortase A in Lactococcus lactis

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