Genetics of healthy ageing

Sylwia Figarska

Genetics of healthy ageing

Vertaalde titel van de bijdrage: Genetica van gezond ouder worden

Sylwia Figarska

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Veroudering gaat samen met een afname van de fysiologische functies. Deze afname van fysiologische functies kan leiden tot de ontwikkeling van leeftijdsgebonden ziekten, zoals cardiovasculaire ziekte (CVD) of chronische obstructieve longziekte (COPD), en uiteindelijk tot de dood. Er zijn grote verschillen in het tempo van veroudering tussen mensen; mensen worden ziek en sterven op verschillende leeftijden. Genetica lijkt een belangrijke rol te spelen in het tempo van veroudering. Uit eerder onderzoek is gebleken dat de variatie in de menselijke levensduur voor ongeveer 30% erfelijk bepaald is. Dit proefschrift richt zich op de genetische factoren die geassocieerd zijn met sterfte in zijn algemeenheid en met sterfte door specifieke oorzaken (cardiovasculaire en COPD-gerelateerde sterfte) in de algemene bevolking.

Vertaalde titel van de bijdrage	Genetica van gezond ouder worden
Originele taal-2	English
Kwalificatie	Doctor of Philosophy
Toekennende instantie	Rijksuniversiteit Groningen
Begeleider(s)/adviseur	Boezen, Hendrika, Supervisor Vonk, Judith, Co-supervisor
Datum van toekenning	26-mei-2014
Plaats van publicatie	[S.l.]
Uitgever	[s.n.]
Gedrukte ISBN's	978-90-367-6994-5
Elektronische ISBN's	978-90-367-6993-8
Status	Published - 2014

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Complete dissertationFinal publisher's version, 4,37 MB
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title = "Genetics of healthy ageing",

abstract = "Ageing is defined as a decline of physiological functions. Decline of physiological functions ultimately lead to the development of age-related diseases, such a cardiovascular disease (CVD) or Chronic Obstructive Pulmonary Disease (COPD), and in consequence to death. Humans age at different pace; they develop a disease and die at different ages. Among factors influencing human lifespan, genetics seem to play an important role, since the variation in human lifespan is heritable for approximately 30\%. This thesis focuses on the genetic factors influencing human all-cause and cause-specific mortality, i.e. cardiovascular and COPD mortality in the general population.",

author = "Sylwia Figarska",

year = "2014",

language = "English",

isbn = "978-90-367-6994-5",

publisher = "[s.n.]",

school = "University of Groningen",

}

TY - BOOK

T1 - Genetics of healthy ageing

AU - Figarska, Sylwia

PY - 2014

Y1 - 2014

N2 - Ageing is defined as a decline of physiological functions. Decline of physiological functions ultimately lead to the development of age-related diseases, such a cardiovascular disease (CVD) or Chronic Obstructive Pulmonary Disease (COPD), and in consequence to death. Humans age at different pace; they develop a disease and die at different ages. Among factors influencing human lifespan, genetics seem to play an important role, since the variation in human lifespan is heritable for approximately 30%. This thesis focuses on the genetic factors influencing human all-cause and cause-specific mortality, i.e. cardiovascular and COPD mortality in the general population.

AB - Ageing is defined as a decline of physiological functions. Decline of physiological functions ultimately lead to the development of age-related diseases, such a cardiovascular disease (CVD) or Chronic Obstructive Pulmonary Disease (COPD), and in consequence to death. Humans age at different pace; they develop a disease and die at different ages. Among factors influencing human lifespan, genetics seem to play an important role, since the variation in human lifespan is heritable for approximately 30%. This thesis focuses on the genetic factors influencing human all-cause and cause-specific mortality, i.e. cardiovascular and COPD mortality in the general population.

M3 - Thesis fully internal (DIV)

SN - 978-90-367-6994-5

PB - [s.n.]

CY - [S.l.]

ER -

Genetics of healthy ageing

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