Hair cell mechano-transduction: Its influence on the gross mechanical characteristics of a hair cell sense organ

Sietse M. van Netten*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

21 Citaten (Scopus)

Samenvatting

The complex mechanical behaviour of a hair cell bundle appears to be a direct consequence of the gating forces on the individual transduction channels. The mechanical molecular interactions involved in transduction channel gating, therefore, also bear a reciprocal influence, via the hair bundles; on the mechanical properties of accessory structures driving them. This allows for the possibility to investigate, under in vivo conditions, the mechanical gating machinery of ion channels via the dynamics of accessory structures. We have performed such studies on the lateral line relate the mechanics of elementary molecular events to the macroscopical dynamics of an intact organ. (C) 1997 Elsevier Science B.V.

Originele taal-2English
Pagina's (van-tot)43-52
Aantal pagina's10
TijdschriftProgress in Biophysics & Molecular Biology
Volume68
Nummer van het tijdschrift1-3
DOI's
StatusPublished - okt.-1997
Evenement12th International Biophysics Congress - , Netherlands
Duur: 12-aug.-199616-aug.-1996

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