HIGH-MOLECULAR-WEIGHT COPOLYMERS OF L-LACTIDE AND EPSILON-CAPROLACTONE AS BIODEGRADABLE ELASTOMERIC IMPLANT MATERIALS

DW GRIJPMA, GJ ZONDERVAN, AJ PENNINGS

OnderzoeksoutputAcademicpeer review

163 Citaten (Scopus)

Samenvatting

High molecular weight copolymers of L-lactide and epsilon-caprolactone have been synthesized by ring opening copolymerization with stannous octoate as catalyst. The good mechanical properties of the 50/50 copolymers make it a suitable material for biomedical applications such as nerve guides etc., where degradation of the elastomeric implant is required. In contrast to the frequently used MDI containing polyurethanes, degradation products of the P(LLA-epsilon-CL) are non toxic. The use of such a material is therefore preferable.

Originele taal-2English
Pagina's (van-tot)327-333
Aantal pagina's7
TijdschriftPolymer Bulletin
Volume25
Nummer van het tijdschrift3
StatusPublished - mrt-1991

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