TY - JOUR
T1 - High prevalence of malnutrition and nutrition impact symptoms in older patients with cancer
T2 - Results of a Brazilian multicenter study
AU - de Pinho, Nivaldo B.
AU - Martucci, Renata B.
AU - Rodrigues, Viviane D.
AU - D'Almeida, Cristiane A.
AU - Thuler, Luiz C. S.
AU - Saunders, Claudia
AU - Jager-Wittenaar, Harriet
AU - Peres, Wilza A. F.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Background Malnutrition in cancer is an independent factor associated with negative clinical outcomes. The objective of this study was to evaluate the prevalence of malnutrition across different age groups in patients with cancer in Brazil and to identify associations with nutrition impact symptoms (NIS). Methods In this observational, cross-sectional, multicenter study, the authors evaluated 4783 patients with cancer aged >= 20 years who were admitted to 45 public hospitals in Brazil. Nutritional status, nutritional risk, and NIS were evaluated using the Patient-Generated Subjective Global Assessment. Results More than one-fourth (25.5%) of all participants were aged >= 65 years. In patients aged >= 65 years, the prevalence of moderate/suspected and severe malnutrition was 55%, it was 45.4% in those aged 51 to 64 years, and it was 36.1% in those aged = 65 years were no appetite (odds ratio [OR], 1.90; 95% CI, 1.62-2.22; P <.05) and dry mouth (OR, 1.40; 95% CI, 1.1-1.67; P <.05). In patients between ages 51 and 64 years, compared with those aged = 65 years who have cancer. The occurrence of NIS was higher in the population aged >50 years than in those aged
AB - Background Malnutrition in cancer is an independent factor associated with negative clinical outcomes. The objective of this study was to evaluate the prevalence of malnutrition across different age groups in patients with cancer in Brazil and to identify associations with nutrition impact symptoms (NIS). Methods In this observational, cross-sectional, multicenter study, the authors evaluated 4783 patients with cancer aged >= 20 years who were admitted to 45 public hospitals in Brazil. Nutritional status, nutritional risk, and NIS were evaluated using the Patient-Generated Subjective Global Assessment. Results More than one-fourth (25.5%) of all participants were aged >= 65 years. In patients aged >= 65 years, the prevalence of moderate/suspected and severe malnutrition was 55%, it was 45.4% in those aged 51 to 64 years, and it was 36.1% in those aged = 65 years were no appetite (odds ratio [OR], 1.90; 95% CI, 1.62-2.22; P <.05) and dry mouth (OR, 1.40; 95% CI, 1.1-1.67; P <.05). In patients between ages 51 and 64 years, compared with those aged = 65 years who have cancer. The occurrence of NIS was higher in the population aged >50 years than in those aged
KW - malnutrition
KW - nutrition impact symptoms
KW - nutritional risk
KW - nutritional screening
KW - older adult
KW - Patient-Generated Subjective Global Assessment (PG-SGA)
KW - SUBJECTIVE GLOBAL ASSESSMENT
KW - QUALITY-OF-LIFE
KW - CELLULAR SENESCENCE
KW - WEIGHT-LOSS
KW - DRY MOUTH
KW - PHASE-II
KW - TRIAL
KW - CHEMOTHERAPY
KW - SARCOPENIA
KW - ANOREXIA
U2 - 10.1002/cncr.32437
DO - 10.1002/cncr.32437
M3 - Article
SN - 0008-543X
VL - 126
SP - 156
EP - 164
JO - Cancer
JF - Cancer
IS - 1
ER -