Hyperglycaemia in critically ill patients: marker or mediator of mortality?

Anouk M. Corstjens, Iwan C. C. van der Horst, A. B. Johan Groeneveld, Felix Zijlstra, Jaap E. Tulleken, Jack J. M. Ligtenberg*, Jan Zijlstra

*Corresponding author voor dit werk

    Onderzoeksoutputpeer review

    57 Citaten (Scopus)
    242 Downloads (Pure)

    Samenvatting

    Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of hyperglycaemia in critically ill patients, using stringent criteria, approaches 100%. An unambiguous negative correlation between hyperglycaemia and mortality has been described in various groups of critically ill patients. Although the available evidence remains inconsistent, there appears to be a favourable effect of glucose regulation. This effect on morbidity and mortality depends on patient characteristics. To be able to compare results of future studies involving glucose regulation, better definitions of hyperglycaemia ( and consequently of normoglycaemia) and patient populations are needed.

    Originele taal-2English
    Artikelnummer216
    Aantal pagina's5
    TijdschriftCritical Care
    Volume10
    Nummer van het tijdschrift3
    DOI's
    StatusPublished - 2006

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