Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: A retrospective study

Konstantina Gartzonika; John Rossen; Hercules Sakkas; Sigrid Rosema; Efthalia Priavali; Alexander Friedrich; Stamatina Levidiotou; Erik Bathoorn

doi:10.1016/j.cmi.2017.12.007

Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: A retrospective study

Konstantina Gartzonika, John Rossen, Hercules Sakkas, Sigrid Rosema, Efthalia Priavali, Alexander Friedrich, Stamatina Levidiotou, Erik Bathoorn

Onderzoeksoutput › Academic › peer review

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We identified the first nosocomial outbreak of KPC-9-producing isolates. Genetic comparison between our isolates and isolates of KPC-KP ST258 associated with Greece indicated that blaKPC-9 may have been replaced by blaKPC-2 on the pKpQiL- plasmid in KPC-KP ST258. The KPC-9-KP outbreak cluster is closely related to the KPC-2-KP outbreak in Greece. Screening for specific sublineages of KPC-KP ST258 by molecular tests may become an important tool in outbreak investigation.

Originele taal-2	English
Pagina's (van-tot)	558-560
Aantal pagina's	3
Tijdschrift	Clinical Microbiology and Infection
Volume	24
Nummer van het tijdschrift	5
Vroegere onlinedatum	21-dec.-2017
DOI's	https://doi.org/10.1016/j.cmi.2017.12.007
Status	Published - mei-2018
Extern gepubliceerd	Ja

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Identification of a KPC-9-producing Klebsiella pneumoniae
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Gartzonika, K., Rossen, J., Sakkas, H., Rosema, S., Priavali, E., Friedrich, A., Levidiotou, S., & Bathoorn, E. (2018). Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: A retrospective study. Clinical Microbiology and Infection, 24(5), 558-560. https://doi.org/10.1016/j.cmi.2017.12.007

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title = "Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: A retrospective study",

abstract = "We identified the first nosocomial outbreak of KPC-9-producing isolates. Genetic comparison between our isolates and isolates of KPC-KP ST258 associated with Greece indicated that blaKPC-9 may have been replaced by blaKPC-2 on the pKpQiL- plasmid in KPC-KP ST258. The KPC-9-KP outbreak cluster is closely related to the KPC-2-KP outbreak in Greece. Screening for specific sublineages of KPC-KP ST258 by molecular tests may become an important tool in outbreak investigation.",

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author = "Konstantina Gartzonika and John Rossen and Hercules Sakkas and Sigrid Rosema and Efthalia Priavali and Alexander Friedrich and Stamatina Levidiotou and Erik Bathoorn",

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Gartzonika, K, Rossen, J, Sakkas, H, Rosema, S, Priavali, E, Friedrich, A, Levidiotou, S & Bathoorn, E 2018, 'Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: A retrospective study', Clinical Microbiology and Infection, vol. 24, nr. 5, blz. 558-560. https://doi.org/10.1016/j.cmi.2017.12.007

TY - JOUR

T1 - Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece

T2 - A retrospective study

AU - Gartzonika, Konstantina

AU - Rossen, John

AU - Sakkas, Hercules

AU - Rosema, Sigrid

AU - Priavali, Efthalia

AU - Friedrich, Alexander

AU - Levidiotou, Stamatina

AU - Bathoorn, Erik

PY - 2018/5

Y1 - 2018/5

N2 - We identified the first nosocomial outbreak of KPC-9-producing isolates. Genetic comparison between our isolates and isolates of KPC-KP ST258 associated with Greece indicated that blaKPC-9 may have been replaced by blaKPC-2 on the pKpQiL- plasmid in KPC-KP ST258. The KPC-9-KP outbreak cluster is closely related to the KPC-2-KP outbreak in Greece. Screening for specific sublineages of KPC-KP ST258 by molecular tests may become an important tool in outbreak investigation.

AB - We identified the first nosocomial outbreak of KPC-9-producing isolates. Genetic comparison between our isolates and isolates of KPC-KP ST258 associated with Greece indicated that blaKPC-9 may have been replaced by blaKPC-2 on the pKpQiL- plasmid in KPC-KP ST258. The KPC-9-KP outbreak cluster is closely related to the KPC-2-KP outbreak in Greece. Screening for specific sublineages of KPC-KP ST258 by molecular tests may become an important tool in outbreak investigation.

KW - Letter

U2 - 10.1016/j.cmi.2017.12.007

DO - 10.1016/j.cmi.2017.12.007

M3 - Comment/Letter to the editor

C2 - 29274461

SN - 1198-743X

VL - 24

SP - 558

EP - 560

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 5

ER -

Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: A retrospective study

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