Identification of a novel oxygenase capable of regiospecific hydroxylation of D-limonene into (+)-trans-carveol

M. Groeneveld, H. L. van Beek, W. A. Duetz, M. W. Fraaije*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

18 Citaten (Scopus)
75 Downloads (Pure)

Samenvatting

By genome sequencing and analysis, we have been able to identify a gene cluster encoding a four component oxygenase which is able to oxidize D-limonene, L-limonene, cumene, and indole. Heterologous expression of the complete oxygenase system in Pseudomonas putida S12 allowed efficient and highly regiospecific biotransformation of D-limonene into (+)-trans-carveol. The discovered oxygenase represents a promising biocatalyst for the biotechnological valorisation of D-limonene. (C) 2015 Elsevier Ltd. All rights reserved.

Originele taal-2English
Pagina's (van-tot)7263-7267
Aantal pagina's5
TijdschriftTetrahedron
Volume72
Nummer van het tijdschrift46
DOI's
StatusPublished - 17-nov.-2016
Evenement12th Conference on Modern Developments in Biotransformations (Biotrans) - Vienna, Austria
Duur: 1-jan.-2015 → …

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