Treatment of HIV infected patients with antiretroviral drugs often results in the emergence of virus variants with reduced sensitivity to these drugs. However, the viral load often remains partially suppressed below pretherapy levels, which might be explained by a reduced fitness of the drug resistant viral population. This review describes the effects of antiretroviral resistance development on the fitness of the viral population and its clinical implications. Curr Opin Infect Dis 14:23-28. (C) 2001 Lippincott Williams & Wilkins.
|Tijdschrift||Current opinion in infectious diseases|
|Nummer van het tijdschrift||1|
|Status||Published - feb-2001|