Inappropriate Use of Antimicrobials for Lower Respiratory Tract Infections in Elderly Patients: Patient- and Community-Related Implications and Possible Interventions

Inger van Heijl*, Valentijn A. Schweitzer, Lufang Zhang, Paul D. van der Linden, Cornelis H. van Werkhoven, Douwe F. Postma

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

3 Citaten (Scopus)
2 Downloads (Pure)


The elderly are more susceptible to infections, which is reflected in the incidence and mortality of lower respiratory tract infections (LRTIs) increasing with age. Several aspects of antimicrobial use for LRTIs in elderly patients should be considered to determine appropriateness. We discuss possible differences in microbial etiology between elderly and younger adults, definitions of inappropriate antimicrobial use for LRTIs currently found in the literature, along with their results, and the possible negative impact of antimicrobial therapy at both an individual and community level. Finally, we propose that both antimicrobial stewardship interventions and novel rapid diagnostic techniques may optimize antimicrobial use in elderly patients with LRTIs.

Originele taal-2English
Pagina's (van-tot)389-398
Aantal pagina's10
TijdschriftDrugs & Aging
Nummer van het tijdschrift5
StatusPublished - mei-2018
Extern gepubliceerdJa

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