Investigation of Friction-induced Damage to the Pig Cornea

Raquel da Cruz Barros; Theo G. Van Kooten; Deepak Halenahally Veeregowda

doi:10.1016/j.jtos.2015.05.004

Investigation of Friction-induced Damage to the Pig Cornea

Raquel da Cruz Barros, Theo G. Van Kooten, Deepak Halenahally Veeregowda^*

^*Corresponding author voor dit werk

Onderzoeksoutput: Article › Academic › peer review

7 Citaten (Scopus)

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Mechanical friction causes damage to the cornea. A friction measurement device with minimal intervention with the pig cornea tear film revealed a low friction coefficient of 0.011 in glycerine solution. Glycerine molecules presumably bind to water, mucins, and epithelial cells and therewith improve both squeeze film and boundary lubrication. Using confocal microscopy, we determined that glycerine solution reduced damage to epithelial cells by 50% compared with the phosphate buffer saline.

Originele taal-2	English
Pagina's (van-tot)	315-320
Aantal pagina's	6
Tijdschrift	Ocular Surface
Volume	13
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1016/j.jtos.2015.05.004
Status	Published - okt.-2015

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Investigation of Friction-induced Damage to the Pig Cornea
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title = "Investigation of Friction-induced Damage to the Pig Cornea",

abstract = "Mechanical friction causes damage to the cornea. A friction measurement device with minimal intervention with the pig cornea tear film revealed a low friction coefficient of 0.011 in glycerine solution. Glycerine molecules presumably bind to water, mucins, and epithelial cells and therewith improve both squeeze film and boundary lubrication. Using confocal microscopy, we determined that glycerine solution reduced damage to epithelial cells by 50% compared with the phosphate buffer saline.",

keywords = "confocal microscopy, cornea, friction device, glycerine, ARTIFICIAL TEARS, OCULAR SURFACE, IN-VIVO, LUBRICANT",

author = "{da Cruz Barros}, Raquel and {Van Kooten}, {Theo G.} and Veeregowda, {Deepak Halenahally}",

year = "2015",

month = oct,

doi = "10.1016/j.jtos.2015.05.004",

language = "English",

volume = "13",

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T1 - Investigation of Friction-induced Damage to the Pig Cornea

AU - da Cruz Barros, Raquel

AU - Van Kooten, Theo G.

AU - Veeregowda, Deepak Halenahally

PY - 2015/10

Y1 - 2015/10

N2 - Mechanical friction causes damage to the cornea. A friction measurement device with minimal intervention with the pig cornea tear film revealed a low friction coefficient of 0.011 in glycerine solution. Glycerine molecules presumably bind to water, mucins, and epithelial cells and therewith improve both squeeze film and boundary lubrication. Using confocal microscopy, we determined that glycerine solution reduced damage to epithelial cells by 50% compared with the phosphate buffer saline.

AB - Mechanical friction causes damage to the cornea. A friction measurement device with minimal intervention with the pig cornea tear film revealed a low friction coefficient of 0.011 in glycerine solution. Glycerine molecules presumably bind to water, mucins, and epithelial cells and therewith improve both squeeze film and boundary lubrication. Using confocal microscopy, we determined that glycerine solution reduced damage to epithelial cells by 50% compared with the phosphate buffer saline.

KW - confocal microscopy

KW - cornea

KW - friction device

KW - glycerine

KW - ARTIFICIAL TEARS

KW - OCULAR SURFACE

KW - IN-VIVO

KW - LUBRICANT

U2 - 10.1016/j.jtos.2015.05.004

DO - 10.1016/j.jtos.2015.05.004

M3 - Article

SN - 1542-0124

VL - 13

SP - 315

EP - 320

JO - Ocular Surface

JF - Ocular Surface

IS - 4

ER -

Investigation of Friction-induced Damage to the Pig Cornea

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