Iron deficiency after kidney transplantation

Joanna Sophia J Vinke, Marith I Francke, Michele F Eisenga, Dennis A Hesselink, Martin H de Borst*

*Bijbehorende auteur voor dit werk

Onderzoeksoutputpeer review

10 Citaten (Scopus)
86 Downloads (Pure)


Iron deficiency (ID) is highly prevalent in kidney transplant recipients (KTRs) and has been independently associated with an excess mortality risk in this population. Several causes lead to ID in KTRs, including inflammation, medication and an increased iron need after transplantation. Although many studies in other populations indicate a pivotal role for iron as a regulator of the immune system, little is known about the impact of ID on the immune system in KTRs. Moreover, clinical trials in patients with chronic kidney disease or heart failure have shown that correction of ID, with or without anaemia, improves exercise capacity and quality of life, and may improve survival. ID could therefore be a modifiable risk factor to improve graft and patient outcomes in KTRs; prospective studies are warranted to substantiate this hypothesis.

Originele taal-2English
Pagina's (van-tot)1976-1985
Aantal pagina's10
TijdschriftNephrology, Dialysis, Transplantation
Nummer van het tijdschrift11
Vroegere onlinedatum10-sep.-2020
StatusPublished - nov.-2021

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