Isomeric effects in ion-induced fragmentation of alpha- and beta-alanine

P. Sobocinski*, S. Bari, J. Postma, F. Alvarado, R. Hoekstra, B. Manil, J. Rangama, V. Bernigaud, B. A. Huber, T. Schlatholter

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

3 Citaten (Scopus)

Samenvatting

We have investigated the dissociation of alpha- and beta- alanine following impact of slow multicharged ions, namely He(+), He(2+), O(5+) and Xe(20+) at 10 keV per charge unit. The collision products were analyzed using a reflectron-type time-of-flight mass spectrometer. In general, for a given projectile, ionization of both alanine-isomers gives rise to similar fragmentation patterns. However, significantly different peak intensities are observed for fragments with mass over charge ratios (m/q) of 30 and 44 amu. These differences can be explained in terms of isomer geometry and fragment stability. By analyzing the fragment kinetic energies, we found that protons as well as ionic oxygen fragments are sufficiently energetic (up to 200 eV for Xe(20+)) to induce further damage in a biological environment.

Originele taal-2English
TitelRADIATION DAMAGE IN BIOMOLECULAR SYSTEMS
RedacteurenKG McGuigan, K Tokesi, B Sulik
Plaats van productieBRISTOL
UitgeverijIOP PUBLISHING LTD
Aantal pagina's6
ISBN van geprinte versie*****************
DOI's
StatusPublished - 2008
EvenementCOST Action P9 Meeting on Radiation Damage in Biomolecular Systems - , Ireland
Duur: 19-jul-200722-jul-2007

Publicatie series

NaamJournal of Physics Conference Series
UitgeverijIOP PUBLISHING LTD
Volume101
ISSN van geprinte versie1742-6588

Other

OtherCOST Action P9 Meeting on Radiation Damage in Biomolecular Systems
Land/RegioIreland
Periode19/07/200722/07/2007

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