Light-induced molecular rotation triggers on-demand release from liposomes

Laís Ribovski; Qihui Zhou; Jiawen Chen; Ben L Feringa; Patrick van Rijn; Inge S Zuhorn

doi:10.1039/d0cc02499f

Light-induced molecular rotation triggers on-demand release from liposomes

Laís Ribovski, Qihui Zhou, Jiawen Chen, Ben L Feringa, Patrick van Rijn^*, Inge S Zuhorn

^*Corresponding author voor dit werk

Onderzoeksoutput: Article › Academic › peer review

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Controllable molecular release from delivery vehicles is essential to successfully reduce drug toxicity and improve therapeutic efficacy. Light-powered hydrophobic molecular motors were therefore incorporated in liposomes to use molecular rotation to facilitate on-demand release. The extent of the release was precisely controlled by irradiation times, providing a simple yet sophisticated responsive molecular nanocarrier. This journal is

Originele taal-2	English
Pagina's (van-tot)	8774-8777
Aantal pagina's	4
Tijdschrift	Chemical communications (Cambridge, England)
Volume	56
Nummer van het tijdschrift	62
Vroegere onlinedatum	3-jul.-2020
DOI's	https://doi.org/10.1039/d0cc02499f
Status	Published - 11-aug.-2020

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10.1039/d0cc02499fLicentie: CC BY

Light-induced molecular rotation triggers on-demand release from liposomes† Final publisher's version, 1,81 MBLicentie: CC BY

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title = "Light-induced molecular rotation triggers on-demand release from liposomes",

abstract = "Controllable molecular release from delivery vehicles is essential to successfully reduce drug toxicity and improve therapeutic efficacy. Light-powered hydrophobic molecular motors were therefore incorporated in liposomes to use molecular rotation to facilitate on-demand release. The extent of the release was precisely controlled by irradiation times, providing a simple yet sophisticated responsive molecular nanocarrier. This journal is ",

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AU - Ribovski, Laís

AU - Zhou, Qihui

AU - Chen, Jiawen

AU - Feringa, Ben L

AU - van Rijn, Patrick

AU - Zuhorn, Inge S

PY - 2020/8/11

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N2 - Controllable molecular release from delivery vehicles is essential to successfully reduce drug toxicity and improve therapeutic efficacy. Light-powered hydrophobic molecular motors were therefore incorporated in liposomes to use molecular rotation to facilitate on-demand release. The extent of the release was precisely controlled by irradiation times, providing a simple yet sophisticated responsive molecular nanocarrier. This journal is

AB - Controllable molecular release from delivery vehicles is essential to successfully reduce drug toxicity and improve therapeutic efficacy. Light-powered hydrophobic molecular motors were therefore incorporated in liposomes to use molecular rotation to facilitate on-demand release. The extent of the release was precisely controlled by irradiation times, providing a simple yet sophisticated responsive molecular nanocarrier. This journal is

KW - NANOMEDICINE

KW - DELIVERY

KW - MOTORS

U2 - 10.1039/d0cc02499f

DO - 10.1039/d0cc02499f

M3 - Article

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JO - Chemical communications (Cambridge, England)

JF - Chemical communications (Cambridge, England)

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Light-induced molecular rotation triggers on-demand release from liposomes

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