Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

Yu Xuan Lyu*, Qiang Fu, Dominika Wilczok, Kejun Ying, Aaron King, Adam Antebi, Aleksandar Vojta, Alexandra Stolzing, Alexey Moskalev, Anastasia Georgievskaya, Andrea B. Maier, Andrea Olsen, Anja Groth, Anna Katharina Simon, Anne Brunet, Aisyah Jamil, Anton Kulaga, Asif Bhatti, Benjamin Yaden, Bente Klarlund PedersenBjörn Schumacher, Boris Djordjevic, Brian Kennedy, Chieh Chen, Christine Yuan Huang, Christoph U. Correll, Coleen T. Murphy, Collin Y. Ewald, Danica Chen, Dario Riccardo Valenzano, Dariusz Sołdacki, David Erritzoe, David Meyer, David A. Sinclair, Eduardo Nunes Chini, Emma C. Teeling, Eric Morgen, Eric Verdin, Erik Vernet, Estefano Pinilla, Evandro F. Fang, Evelyne Bischof, Evi M. Mercken, Fabian Finger, Folkert Kuipers, Frank W. Pun, Gabor Gyülveszi, Gabriele Civiletto, James L. Kirkland, Liesbeth M. Veenhoff, Morten Scheibye-Knudsen, Daniela Bakula

*Corresponding author voor dit werk

OnderzoeksoutputAcademicpeer review

2 Citaten (Scopus)

Samenvatting

The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan.

Originele taal-2English
Pagina's (van-tot)12955-12976
Aantal pagina's22
TijdschriftAging
Volume16
Nummer van het tijdschrift20
DOI's
StatusPublished - 31-okt.-2024

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