Samenvatting
Objective. To determine the predictive value of lumbar skeletal muscle mass and density for postoperative outcomes in older women with advanced stage ovarian cancer.
Methods. A multicenter, retrospective cohort study was performed in women >= 70 years old receiving surgery for primary, advanced stage ovarian cancer. Skeletal muscle mass and density were assessed in axial CT slices on level L3. Low skeletal muscle mass was defined as skeletal muscle index < 38.50 cm(2)/m(2). Low skeletal muscle density was defined as one standard deviation below the mean (muscle attenuation < 22.55 Hounsfield Units). The primary outcome was any postoperative complication
Results. In analysis of 213 patients, preoperative low skeletal muscle density was associated with postopera-tive complications = 2).
Conclusion. Low skeletal muscle density, as a proxy of muscle quality, is associated with poor postoperative outcomes in older patients with advanced stage ovarian cancer. These findings can contribute to postoperative risk assessment and clinical decision making. (C) 2021 The Author(s). Published by Elsevier Inc.
Originele taal-2 | English |
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Pagina's (van-tot) | 360-367 |
Aantal pagina's | 8 |
Tijdschrift | Gynecologic Oncology |
Volume | 162 |
Nummer van het tijdschrift | 2 |
DOI's | |
Status | Published - aug.-2021 |